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Science

Q Energy - Drink Healthy Ambassadors Amanda Ammar and Sandra Walter (Scott Robarts Photography). Vancouver Endurance Club Coach, Paul Cross.

Summaries and Links to Scientific Studies on Quercetin 

Quercetin Improves Exercise Performance
Quercetin use for two weeks was associated with significant increase in blood plasma quercetin levels and significant improvement (2.9%) in 12-min treadmill time trial performance as well as a modest (4.1%) but statistically insignificant increases in the relative copy number of mitochondrial DNA and messenger RNA levels of four genes related to mitochondrial biogenesis.

Quercetin's Influence on Exercise Performance and Muscle Mitochondrial Biogenesis
Med Sci Sports Exerc. 2009 Nov 13. [Epub ahead of print]. Nieman DC, Williams AS, et al. Departments of Health, Leisure, and Exercise Science Biology; Appalachian State University, Boone, NC.

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Quercetin Increases VO2max and Endurance
Quercetin use for seven days was associated with a 3.9% increase in VO2max along with a substantial 13.2% increase in ride time (bicycle) to fatigue for test subjects.

The dietary flavonoid quercetin increases VO2max and endurance capacity.
Int J Sport Nutr Exerc Metab. 2010 Feb;20(1):56-62. Davis JM, Carlstedt CJ, Chen S, Carmichael MD, Murphy EA.

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Quercetin Increases Endurance and Energy in Laboratory Study
A controlled scientific study on the effect of quercetin feedings in mice resulted in increased mitochondrial biogenesis (the production of mitochondria) in both the brain and muscle of the subjects. The increased mitochondria was associated with increased maximal endurance as well as increased voluntary exercise, suggesting greater energy.

Quercetin increases brain and muscle mitochondrial biogenesis and exercise tolerance.
Am J Physiol Regul Integr Comp Physiol. 2009 Apr;296(4):R1071-7. Epub 2009 Feb 11. Davis JM, Murphy EA, Carmichael MD, Davis B.

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Quercetin Supports Immune Function
Quercetin significantly reduced upper respiratory tract infection incidence in cyclists during the 2-wk period after intensified exercise.

Quercetin reduces illness but not immune perturbations after intensive exercise.
Med Sci Sports Exerc. 2007 Sep;39(9):1561-9. Nieman DC, Henson DA, Gross SJ, Jenkins DP, Davis JM, Murphy EA, Carmichael MD, Dumke CL, Utter AC, McAnulty SR, McAnulty LS, Mayer EP.

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Quercetin Inhibits Rhinovirus Replication
A University of Michigan study indicates that "quercetin may be beneficial in the treatment of viral infections" by virtue of its ability to inhibit the replication of the rhinovirus, the virus which is responsible for the vast majority of common colds.

S. Ganesan, MS, S. Chattoraj, MS, A.N. Faris, Ph.D., A. Comstock, BS, U. Sajjan, PhD  
University of Michigan - Ann Arbor, MI/US 

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Quercetin Inhibits Fat Cells' Ability To Produce Fat
The ability of fat cells to produce fat is inhibited by 15-18% by resveratrol or quercetin alone, but when combined, this inhibitory effect climbs to 73%, nearly a five-fold difference.

 Enhanced inhibition of adipogenesis and induction of apoptosis in 3T3-L1 adipocytes with combinations of resveratrol and quercetin. 
Yang JY, Della-Fera MA, Rayalam S, Ambati S, Hartzell DL, Park HJ, Baile CA. 

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Quercetin helps prevent viral illnesses like colds and flu after physical exertion.
In testimony submitted to the House Armed Services Committee, United States House of Representatives, Dr Tony Tether, director of Defence Advanced Research Projects Agency, stated:

"Among quercetin’s many potential benefits is illness prevention. In a randomized, placebo-controlled study, quercetin helped prevent viral illnesses like colds and flu after physical exertion. Following a strenuous three-day exercise routine, 50% of the control group became ill with colds and flu, whereas only 5% of the quercetin-supplemented group did.”